Stem Cell Transplantation
Our professional team connects you with doctors specializing in bone marrow, stem cell, and cord blood transplantation and CAR-T cell therapy.

Stem Cell Transplantation

Bilyana Health is a health tourism intermediary organization that brings together patients who choose Turkey for a healthier life with Turkey's leading clinics, hospitals, and doctors. Our professional team connects you with doctors specializing in bone marrow, stem cell, and cord blood transplantation and CAR-T cell therapy. We provide patients and their relatives with easy access to a wide range of services, including consultancy, transfer, accommodation, emotional support, and second medical opinions.

Autologous Stem Cell Transplantation Allogeneic Stem Cell Transplantation How are stem cells collected for bone marrow transplantation? After Bone Marrow Transplantation

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Autologous Stem Cell Transplantation

• The process involves collecting stem cells from the individual, freezing and storing them in nitrogen tanks at -80 and -196 degrees Celsius, and then administering them to the individual after high-dose chemotherapy.

• The primary goal here is to administer high-dose chemotherapy to the patie

• Autologous Stem Cell Transplantation is performed for lymphomas, multiple myeloma, acute leukemias, and germ cell tumors.

Allogeneic Stem Cell Transplantation

• It is the process of obtaining stem cells from the patient’s sibling, if no sibling donor is available, from relatives, and if no relatives can be found, from an unrelated donor.

• What is important is tissue compatibility.

• It is the process of administering hematopoietic stem cells from a healthy donor to the recipient after high-dose chemotherapy, with the aim of destroying malignant cells.

• Allogeneic Stem Cell Transplantation is applied to patients with acute leukemias (AML-ALL), aplastic anemia, Hodgkin and non-Hodgkin lymphomas, chronic leukemias (CML-CLL), and thalassemia.

How are stem cells collected for bone marrow transplantation?

Stem cell collection is performed in two main ways for bone marrow transplantation.

The first method involves collecting stem cells directly from the hip bone under anesthesia in an operating room. Temporary drops in blood values might occur depending on the volume collected, but these typically resolve within 1-2 weeks and are not permanent.

The second method involves administering medication to the donor twice daily for five days, which causes the stem cells to move from the bone marrow into the bloodstream. The collection is then done via a machine without anesthesia. To date, no adverse effects of the medication on the donor have been reported.

After about 20 years of global use of these medications in thousands of transplants, no permanent harm to donors has been observed. During and shortly after the medication course, there may be an increase in white blood cell count and bone pain, which can be managed with simple pain relievers.

For bone marrow donors, blood group compatibility is not required. If the blood groups are different, the collected product is processed before being given to the patient. Following a successful transplant, the recipient's blood group will typically match that of the donor.

After Bone Marrow Transplantation

After a bone marrow transplant, patients may experience various situations and side effects. Here are some common occurrences:

1. Changes in Immune System:* Following the transplant, the immune system changes due to the new bone marrow, and immunosuppressive medications may be required. This can increase the risk of infections.

2. Infections:* With a weakened immune system, patients are more vulnerable to infections.

3. Fatigue and Low Energy:* Fatigue is a common side effect and part of the recovery process.

4. Bleeding and Bruising:* The production of blood cells may temporarily decrease, leading to bleeding and bruising.

5. Pain and Discomfort:* Pain and discomfort at the transplant site can occur, and some patients may experience joint or muscle pain as well.

6. Nausea and Vomiting:* Chemotherapy and other treatments may cause nausea.

7. Skin and Oral Sores:* Rashes on the skin and sores in the mouth may develop.

8. Emotional and Psychological Challenges:* The recovery process can be stressful and may lead to emotional difficulties.

Experiences after a bone marrow transplant can vary from person to person, and doctors create a personalized care plan to manage the process. If you have specific symptoms or concerns after a bone marrow transplant, it's important to discuss them with your healthcare team.